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Exam-style practice (harder): Biology multiple choice quiz

14 questions. Pick an answer and you'll see why right away. Options are shuffled each attempt, and the review at the end links each missed question to the dot point to revise.

  1. Two adults, P and Q, each drank the same glucose solution at time 0. Blood glucose and insulin were measured for 3 hours.

    Time (min) P glucose (mmol/L) P insulin (relative units) Q glucose (mmol/L) Q insulin (relative units)
    0 5.0 10 5.2 30
    30 8.2 60 11.5 55
    60 6.4 40 12.8 70
    120 5.1 12 11.9 75
    180 5.0 10 10.8 72

    Which conclusion is best supported by the data?

  2. Haemophilia A is inherited as an X-linked recessive trait. A woman with normal blood clotting, whose father had haemophilia A, has a child with a man who does not have haemophilia A.

    What is the probability that their first child is a son with haemophilia A?

  3. A student suspects that a bacterium causes a leaf-spot disease of bean plants. She:

    1. finds the bacterium in every spotted leaf examined, and not in healthy leaves
    2. grows the bacterium in pure culture on agar
    3. inoculates healthy bean plants with the pure culture, and they develop leaf spot.

    Which further step is needed to satisfy Koch's postulates?

  4. Part of the template strand of a gene reads 3'-TAC CGA ACC TTT-5'.

    mRNA codon Amino acid
    AUG Met (start)
    GCU Ala
    UGG Trp
    UGU Cys
    UGA Stop
    AAA Lys

    A substitution changes the third triplet of the template strand from ACC to ACT. What is the most likely effect on the polypeptide?

  5. The table shows data for one region over five years.

    Year Measles vaccination coverage (%) Measles cases per 100 000 people
    1 95 0.2
    2 94 0.3
    3 91 1.1
    4 88 6.4
    5 86 14.9

    Which statement is best supported by the data?

  6. A person sees distant objects clearly but has a near point of 60 cm (a typical near point is about 25 cm).

    Which option correctly identifies the corrective lens and the reason it is needed?

  7. A student investigates the effect of temperature on the rate of fermentation by yeast. For each of five temperatures (15, 25, 35, 45 and 55 °C) she heats a beaker of water to that temperature, places a tube of yeast in sugar solution in it, removes the beaker from the hotplate and collects CO₂ for 10 minutes. Each temperature is tested three times.

    Which change would most improve the validity of this investigation?

  8. A culture of bacteria was treated with an antibiotic on day 0. The antibiotic had fully broken down by day 2.

    Day Total bacteria (millions) Resistant to the antibiotic (%)
    0 (before treatment) 100 2
    2 8 25
    6 60 20

    Which statement is supported by the data?

  9. After a deep, dirty cut, a person who has never been vaccinated against tetanus is given an injection of antibodies against tetanus toxin (antitoxin).

    Which statement best describes the protection this injection provides?

  10. Two healthy volunteers emptied their bladders. At time 0, one drank 1 L of water and the other drank 1 L of concentrated salt solution. Urine was collected every 30 minutes.

    Time (min) Urine volume, water drink (mL) Urine volume, salt drink (mL)
    0 to 30 60 40
    30 to 60 320 35
    60 to 90 260 30
    90 to 120 90 30

    Which explanation best accounts for the difference between 30 and 60 minutes?

  11. A cohort study followed 2000 smokers and 3000 non-smokers for 10 years. During the study, 60 of the smokers and 15 of the non-smokers developed disease X.

    How many times greater was the incidence of disease X in smokers than in non-smokers?

  12. A diploid animal cell in G1 contains 12 pg (picograms) of DNA. The cell completes interphase and then meiosis.

    What is the DNA content of each cell at the end of meiosis I and at the end of meiosis II?

  13. Assume each band in a DNA profile is inherited from one parent. The table shows band sizes (kb) for a child, the child's mother and three men.

    Person Band sizes (kb)
    Child 2.1, 3.4, 5.0, 6.2
    Mother 2.1, 4.0, 5.0, 7.5
    Man 1 3.4, 4.0, 6.2, 8.0
    Man 2 3.4, 5.0, 6.8, 7.5
    Man 3 2.1, 5.0, 6.2, 8.0

    Which man could be the biological father?

  14. In a replication of Pasteur's experiment, nutrient broth is boiled in several different containers.

    Which result would give the strongest evidence against spontaneous generation?

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